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PubMed · 3610638

Comparison of risk estimates using life-table methods.

R E Sullivan·P S Weng
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Abstract

Risk estimates promulgated by various radiation protection authorities in recent years have become increasingly more complex. Early "integral" estimates in the form of health effects per 0.01 person-Gy (per person-rad) or per 10(4) person-Gy (per 10(6) person-rad) have tended to be replaced by "differential" estimates which are age- and sex-dependent and specify both minimum induction (latency) and duration of risk expression (plateau) periods. These latter types of risk estimate must be used in conjunction with a life table in order to reduce them to integral form. In this paper, the life table has been used to effect a comparison of the organ and tissue risk estimates derived in several recent reports. In addition, a brief review of life-table methodology is presented and some features of the models used in deriving differential coefficients are discussed. While the great number of permutations possible with dose-response models, detailed risk estimates and proposed projection models precludes any unique result, the reduced integral coefficients are required to conform to the linear, absolute-risk model recommended for use with the integral risk estimates reviewed.

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Actuarial AnalysisDose-Response Relationship, RadiationFemaleHumansMaleMathematicsNeoplasms, Radiation-InducedRiskComparative StudyJournal ArticleResearch Support, Non-U.S. Gov't

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R E Sullivan, P S Weng. 1987. Comparison of risk estimates using life-table methods.. https://doi.org/10.1097/00004032-198708000-00002

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