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Lectin binding in retinoblastoma.

D S Bardenstein·M M Rodrigues·J Alroy·S Brownstein
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Abstract

Lectins were used as cytochemical probes to examine the relationship between normal retina and retinoblastoma. Cases of retinoblastoma in which there were either Flexner-Wintersteiner rosettes or fleurettes accompanied by nontumorous retina were studied with ten biotinylated lectins. Pineal and ocular tumors from cases of trilateral retinoblastoma were also studied. Con-A, LCA, PNA, WGA and RCA-I labeled tissue of each type to varying degrees, while BS-I, DBA, SBA, S-WGA and UEA-I bound neither tumor nor retina. The high degree of binding homology suggests biochemical as well as structural similarities between these tissues.

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Eye NeoplasmsHumansLectinsReference ValuesRetinaRetinoblastomaRosette FormationJournal ArticleResearch Support, Non-U.S. Gov't

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BibTeXRIS

D S Bardenstein, M M Rodrigues, J Alroy, S Brownstein. 1987. Lectin binding in retinoblastoma.. https://doi.org/10.3109/02713688709034887

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