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Ectopic prolactin secretion from a gonadoblastoma.

W H Hoffman·R R Gala·K Kovacs·M G Subramanian
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Abstract

A 6.5-year-old girl developed isosexual, pseudoprecocious puberty secondary to a gonadoblastoma. The tumor was found to produce and secrete both immunoassayable and bioassayable prolactin based on immunohistochemical techniques and the presence of a prolactin gradient between the tumor vein and peripheral vein. The source of the prolactin was a Sertoli-like cell. Neither growth hormone nor growth hormone-releasing hormone was detected within the tumor. This case confirms the ectopic production of prolactin by neoplastic tissue.

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ChildDysgerminomaFemaleGrowth HormoneHormones, EctopicHumansProlactinJournal ArticleResearch Support, U.S. Gov't, P.H.S.

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W H Hoffman, R R Gala, K Kovacs, M G Subramanian. 1987-12-01. Ectopic prolactin secretion from a gonadoblastoma.. https://doi.org/10.1002/1097-0142(19871201)60%3A11%3C2690%3A%3Aaid-cncr2820601119%3E3.0.co%3B2-j

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