The ectodermal control of mesodermal patterns of differentiation in the developing chick wing.

J S Geduspan; J A MacCabe

doi:10.1016/0012-1606(87)90492-1

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The ectodermal control of mesodermal patterns of differentiation in the developing chick wing.

J S Geduspan·J A MacCabe

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Abstract

The influence of limb ectoderm on the dorso-ventral muscle and skeletal patterns in the chick wing was studied by recombining stage 14-21 limb mesoderm with the same stage ectoderm in dorso-ventrally reversed orientation. Recombinants grafted to the flank of host embryos were allowed to develop for 10 days. Fully developed wings obtained from stage 15-21 donor embryos have at their distal half d-v polarity conforming to the reversed ectoderm and proximally polarity conforming with the mesoderm. The ectodermal effect is generally observed as a bidorsal feather pattern at the autopod and an almost complete d-v reversal of muscle and skeletal patterns. In experimental wings from donor embryos younger than stage 15, the dorso-ventral pattern conforms with the polarity of the limb mesoderm. The results suggest that control of dorso-ventral polarity resides in the mesoderm until the onset of limb development at stage 15. At this stage, the ectoderm acquires dorso-ventral information which it can impose on the mesoderm.

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Animals Cell Differentiation Chick Embryo Ectoderm Feathers Mesoderm Morphogenesis Muscles Wings, Animal Journal Article

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J S Geduspan, J A MacCabe. 1987. The ectodermal control of mesodermal patterns of differentiation in the developing chick wing.. https://doi.org/10.1016/0012-1606(87)90492-1

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