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PubMed · 3681668

Mean residence time in peripheral tissue.

P J McNamara·J C Fleishaker·T L Hayden
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Abstract

The published methods for determining the mean residence time for drugs in peripheral tissue are reviewed in terms of assumptions involved, advantages and disadvantages. A method for determining mean transit time in peripheral tissue is proposed; this may be a more useful indicator of the tissue retention properties for drug compounds.

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Half-LifeHumansModels, BiologicalPharmacokineticsTissue DistributionJournal Article

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P J McNamara, J C Fleishaker, T L Hayden. 1987. Mean residence time in peripheral tissue.. https://doi.org/10.1007/bf01066523

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