[Isolation of alpha-latrotoxin using high-performance liquid chromatography methods].

E I Grebinozhko; A N Nikolaenko

PubMed · 3686702

[Isolation of alpha-latrotoxin using high-performance liquid chromatography methods].

Abstract

alpha-Latrotoxin, a main toxic component of the Latrodectus mactans tredecimguttatus venom is a large polypeptide with molecular weight of 130 KDa. A rapid method is suggested for isolating this protein using high-effective liquid chromatography on chromatograph FPLC ("Pharmacia", Sweden). The isolated protein does not differ from the previously described alpha-latrotoxin in the main physicochemical parameters as well as in physiological properties.

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Animals Arthropod Venoms Chromatography, High Pressure Liquid Lethal Dose 50 Mice Spider Venoms English Abstract Journal Article

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E I Grebinozhko, A N Nikolaenko. [Isolation of alpha-latrotoxin using high-performance liquid chromatography methods].. https://pubmed.ncbi.nlm.nih.gov/3686702/

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