PubMed · 3686790
The source did not provide an abstract. Follow the original record for more information.
Explore connections, maps & timelines
M Shilleto. 1987-09-12. Schistosomus reflexus.. https://doi.org/10.1136/vr.121.11.263-a
Cite the original work for its findings. Save a collection to share your selection of sources.
KEEP EXPLORING
In the mediaeval Dutch manuscript Der naturen bloeme ('On the flowers of nature') by Jacob van Maerlant (circa 1230-circa 1296), an encyclopaedia of descriptions of people, animals, plants and minerals dating from about 1270, many illustrations refer to the text. An intriguing part of the book is called 'Vreemde volkeren' ('Exotic people'). In another manuscript of Van Maerlant, Dit is die istory van Troyen ('The history of Troyes') in the chapter 'De wonderen van het Verre Oosten' ('The miracles of the Far East') the exotic people are also described. These exotic people have many features similar to congenital malformations. 'Hippopodes' are probably based on the lobster claw syndrome, 'Cynocephali' on anencephaly, 'Arimaspi' on cyclopia, 'Blemmyae' on acardiacus, the double-faced on diprosopus, 'Sciopods' on polydactyly and 'Antipodes' on the sirenomelia sequence.
Explore the source record for details and available documents.
BACKGROUND: The great majority of reports dealing with human cyclopia and synophthalmia are derived from fetuses at the end of pregnancy. Thus, data concerning early organization of the ocular anlage in this impressive ocular developmental anomaly are almost completely lacking. We therefore present a 12 week-old synophthalmic fetus. CASE REPORT: After uneventful pregnancy spontaneous abortion occurred. Within the face of the hypotrophic fetus there was a central pigmented ocular anlage with an inferior fissure. A nose (proboscis) was not discernible. Histologically, there were two vesicles caudally which fused to one vesicle cranially. Differentiation was more advanced in the anterior and temporal parts of the anlagen. A coherent inner layer (of the optic cup) was not developed. Trisomy 13 was suspected but could not be proved by FISH-technique. CONCLUSIONS: The fetus demonstrates that fusion of the ocular anlagen is finished at the end of the third gestational month and that synophthalmia/cyclopia is very likely to be associated with maldevelopment of the optic cup. As far as we know there is evidence for the first time that organization of the anlagen improves not only in the posterior to anterior and in the medial to lateral but also in the cranial to caudal direction.