Liver function tests. A study in patients with imaging-demonstrated metastases.

J Mathews; J D Slavin; R P Spencer

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PubMed · 3698434

Liver function tests. A study in patients with imaging-demonstrated metastases.

J Mathews·J D Slavin·R P Spencer

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Abstract

Thirty-eight consecutive patients with liver scan evidence of hepatic metastases (and confirmation by other modalities) had blood levels of lactate dehydrogenase and alkaline phosphatase performed within two weeks. In 38% of the patients with small liver metastases, both alkaline phosphatase and lactate dehydrogenase were in the normal range. Even with large metastases present (one or more lesions over 2.5 cm in diameter), 19% of the patients had both enzyme tests within the normal range. Despite the lower cost of these enzyme assays, they failed to detect hepatic metastases in an appreciable portion of our patients.

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Alkaline Phosphatase Clinical Enzyme Tests Humans L-Lactate Dehydrogenase Liver Neoplasms Radionuclide Imaging Comparative Study Journal Article Research Support, U.S. Gov't, P.H.S.

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J Mathews, J D Slavin, R P Spencer. 1986. Liver function tests. A study in patients with imaging-demonstrated metastases.. https://pubmed.ncbi.nlm.nih.gov/3698434/

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