Indirect spectrophotometric method for determining epicillin.

L J Núñez-Vergara; A Roa; J A Squella; R V González-Barbagelata

PubMed · 3700328

Indirect spectrophotometric method for determining epicillin.

L J Núñez-Vergara·A Roa·J A Squella·R V González-Barbagelata

Abstract

A new UV spectrophotometric assay for determination of epicillin in capsules and plasma is reported. The method is based on the absorptivity of a degradation product obtained from the acidic hydrolysis of the antibiotic. The isolation, identification, individual capsule assays, composite assay, and recovery studies are described. Also, the proposed method is compared with a dc polarographic assay in plasma.

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Ampicillin Capsules Humans Hydrolysis Magnetic Resonance Spectroscopy Polarography Spectrophotometry, Infrared Spectrophotometry, Ultraviolet Journal Article Research Support, Non-U.S. Gov't

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L J Núñez-Vergara, A Roa, J A Squella, R V González-Barbagelata. Indirect spectrophotometric method for determining epicillin.. https://pubmed.ncbi.nlm.nih.gov/3700328/

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