DAPI-inducible common fragile sites.

F Pelliccia; A Rocchi

doi:10.1159/000132272

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DAPI-inducible common fragile sites.

F Pelliccia·A Rocchi

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Abstract

DAPI, a compound specific for the AT bases of DNA, causes gaps and breaks in three human chromosome sites, at the 1q41-1q42 interface, 2q31, and 7p22. It also induces undercondensation of a chromosome site at the 13q21-13q22 interface. The first three sites have the characteristics of "common fragile sites" and are present as gaps and breaks on the chromosomes of seven individuals.

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Base Sequence Chromosome Fragile Sites Chromosome Fragility Female Fluorescent Dyes Humans Indoles Karyotyping Leukocytes Male Journal Article Research Support, Non-U.S. Gov't

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F Pelliccia, A Rocchi. 1986. DAPI-inducible common fragile sites.. https://doi.org/10.1159/000132272

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