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Phenazines with two cationic side chains as potential antimalarials.

S N Sawhney·D W Boykin
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Abstract

1,9-Phenazine-bis(dialkylaminocarboxamides) were prepared for screening as potential antimalarials. No significant activity against Plasmodium berghei was observed. The phenazine targets were prepared from 1,9-phenazinedicarboxylic acid by standard methods. The reaction between 1,9-phenazinedicarboxylic acid and thionyl chloride in the presence of dimethylformamide unexpectedly gave 4-chloro-1,9-phenazinedicarbonyl chloride.

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AnimalsAntimalarialsMalariaMethodsPhenazinesPlasmodium bergheiJournal ArticleResearch Support, U.S. Gov't, Non-P.H.S.

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S N Sawhney, D W Boykin. 1979. Phenazines with two cationic side chains as potential antimalarials.. https://doi.org/10.1002/jps.2600680440

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