A sensitive hemolytic assay for mouse C3.

R Ranken; W D Linscott

doi:10.1016/0022-1759(79)90253-9

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A sensitive hemolytic assay for mouse C3.

R Ranken·W D Linscott

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Abstract

We have developed a sensitive hemolytic assay for mouse C3, utilizing readily available guinea pig complement components and standard techniques, which allows C3 to be detected in mouse serum diluted many thousand-fold. Mouse serum also contains a potent, relatively heat-stable C3-inactivator system, which is largely blocked by Suramin.

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Animals Complement C3 Elapid Venoms Female Hemolytic Plaque Technique Hot Temperature Mice Mice, Inbred Strains Osmolar Concentration Suramin Time Factors Journal Article Research Support, U.S. Gov't, P.H.S.

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R Ranken, W D Linscott. 1979. A sensitive hemolytic assay for mouse C3.. https://doi.org/10.1016/0022-1759(79)90253-9

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