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PubMed · 37701

Vasospastic phenomena in patients treated with beta-adrenoceptor blocking agents.

K Eliasson·L E Lins·K Sundqvist
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Abstract

Twenty-one patients developed Raynaud's phenomenon during treatment with beta-adrenoceptor blocking agents. The vasospastic symptoms were obviously related to the treatment, but their pathogenesis is still controversial. A decrease in cardiac output might explain the phenomenon. According to our very preliminary data an alpha-adrenergic dominance caused by a direct effect on the peripheral circulation seems more probable. Vasospastic symptoms may arise after treatment with both cardioselective and non-selective beta blocking agents. Cautious prescription of beta blocking drugs to patients with preexisting peripheral vascular disease is recommended.

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Adrenergic beta-AntagonistsAlprenololBlood CirculationCardiac OutputFemaleHumansHypertensionMaleMetoprololMiddle AgedPropranololRaynaud DiseaseSkin TemperatureTimololJournal Article

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BibTeXRIS

K Eliasson, L E Lins, K Sundqvist. 1979. Vasospastic phenomena in patients treated with beta-adrenoceptor blocking agents.. https://doi.org/10.1111/j.0954-6820.1979.tb00771.x

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