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PubMed · 3778847

Alpha interferon in human pregnancy.

T Chard·P H Craig·M Menabawey·C Lee
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Abstract

The concentration of interferon-alpha was measured by a specific two-site immunoradiometric assay in a variety of fluids and tissues collected during human pregnancy. Maternal blood and blood and tissues from non-pregnant adults contained little or no interferon-alpha. Fetal blood, fetal organs, placenta, membranes, amniotic fluid and decidua all contained significant and roughly equivalent amounts ranging from 1.1 to 10 u/ml (or per g of tissue). These findings demonstrate that the fetus and its immediate surroundings are permeated with interferon. It is suggested that this may play a role in regulation of the maternal-fetal graft relation.

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Amniotic FluidExtraembryonic MembranesFemaleFetal BloodHumansInterferon Type IPlacentaPregnancyComparative StudyJournal ArticleResearch Support, Non-U.S. Gov't

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BibTeXRIS

T Chard, P H Craig, M Menabawey, C Lee. 1986. Alpha interferon in human pregnancy.. https://doi.org/10.1111/j.1471-0528.1986.tb08635.x

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