Direct evidence for pH-dependent Fc receptors on proximal enterocytes of suckling rat gut.

A E Wild; L J Richardson

doi:10.1007/bf01968284

Home/Archive/PubMed

PubMed · 38137

Direct evidence for pH-dependent Fc receptors on proximal enterocytes of suckling rat gut.

A E Wild·L J Richardson

View original source ↗Export metadata ↓

Abstract

By means of an erythrocyte-antibody rosette technique, Fc receptors, functional at pH 6.0 but not at 7.2, were shown to be present on enterocytes isolated from duodenum and jejunum (but absent from ileum) of 12-20-day-old suckling rats.

Explore related subjects

Animal Population Groups Animals Animals, Suckling Binding Sites Duodenum Hydrogen-Ion Concentration Immunoglobulin Fc Fragments Intestinal Mucosa Intestine, Small Jejunum Rats Rosette Formation Journal Article

Keep this discovery

Explore connections, maps & timelines

BibTeX RIS

A E Wild, L J Richardson. 1979-06-15. Direct evidence for pH-dependent Fc receptors on proximal enterocytes of suckling rat gut.. https://doi.org/10.1007/bf01968284

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

PubMed1979

Segmental distribution of soluble neutral maltase activity in suckling rat intestine. Levels vary independently of membrane-bound maltase and lysosomal enzymes during development.

Explore the source record for details and available documents.

Animal Population Groups↗

PubMed1979

Opposite effects of one and three injections of cortisone or thyroxine on intestinal lactase activity in suckling mice.

A single injection of cortisone or thyroxine to 8-day-old suckling mice initiates a temporary decrease of lactase activity. On the contrary, 3 injections of cortisone or thyroxine provoke a significant increase of lactase activity. It appears that the mechanism which controls the postnatal development of lactase in suckling animals is more complex than expected.

Animal Population Groups↗

PubMed1979

Wild mouse RNA tumor viruses. A nongenetically transmitted virus group closely related to exogenous leukemia viruses of laboratory mouse strains.

Type-C RNA viruses isolated from wild mice are causative of naturally occurring neoplasia and neurologic diseases. Biochemical and immunologic characterization of this virus group revealed that amphotropic viruses isolated from wild mice trapped in separate geographical areas are indistinguishable, whereas amphotropic and ecotropic viruses naturally infecting the same animal are env gene variants. Molecular hybridization studies established that neither host range variant is endogenous to the Mus musculus genome, although each demonstrates partial nucleotide sequence homology. Wild mouse type-C viruses exhibited much closer molecular and antigenic relatedness to the exogenous virus subgroup (Friend-, Moloney-, and Rauscher-MuLV) than to prototype endogenous viruses isolated from laboratory mouse strains. The evidence indicates that exogenous mouse type-C viruses have been maintained in nature over a long period of evolution as a separate virus group, causative of tumors in mice by a mechanism solely involving their transmission as infectious agents.

Animal Population Groups↗