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A review focusing on mechanisms and ecological risks of enrichment and propagation of antibiotic resistance genes and mobile genetic elements by microplastic biofilms.

Ranran Zhou·Xirong Huang·Zhongtang Xie·Zhuhong Ding·Hengchen Wei·Qijie Jin
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Abstract

Microplastics (MPs) are emerging ubiquitous pollutants in aquatic environment and have received extensive global attention. In addition to the traditional studies related to the toxicity of MPs and their carrier effects, their unique surface-induced biofilm formation also increases the ecotoxicity potential of MPs from multiple perspectives. In this review, the ecological risks of MPs biofilms were summarized and assessed in detail from several aspects, including the formation and factors affecting the development of MPs biofilms, the selective enrichment and propagation mechanisms of current pollution status of antibiotic resistance genes (ARGs) and mobile genetic elements (MGEs) in MPs biofilms, the dominant bacterial communities in MPs biofilms, as well as the potential risks of ARGs and MGEs transferring from MPs biofilms to aquatic organisms. On this basis, this paper also put forward the inadequacy and prospects of the current research and revealed that the MGEs-mediated ARG propagation on MPs under actual environmental conditions and the ecological risk of the transmission of ARGs and MGEs to aquatic organisms and human beings are hot spots for future research. Relevant research from the perspective of MPs biofilm should be carried out as soon as possible to provide support for the ecological pollution prevention and control of MPs.

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BiofilmsMicroplasticsInterspersed Repetitive SequencesDrug Resistance, MicrobialWater Pollutants, ChemicalAntibiotic resistance geneAquatic organismBiofilmDisseminationMicroplasticMobile genetic elementsJournal ArticleReview

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Ranran Zhou, Xirong Huang, Zhongtang Xie, Zhuhong Ding, Hengchen Wei, Qijie Jin. 2024-03-16. A review focusing on mechanisms and ecological risks of enrichment and propagation of antibiotic resistance genes and mobile genetic elements by microplastic biofilms.. https://doi.org/10.1016/j.envres.2024.118737

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