PubMed · 3863864
Diffuse mandibular enlargement.
Abstract
Paget's disease of the jaw has the following characteristics: slow progression of jaw enlargement; bilateral jaw involvement; often polyostotic, but not generalized skeletal disease; diffuse, irregular radiopaque areas of the jaw; elevated serum alkaline phosphatase level; and a biopsy specimen showing thick, irregular bone trabeculae with a mosaic pattern of reversal lines and numerous osteoblasts and osteoclasts in a fibrovascular stroma. Management of a patient with Paget's disease of bone usually is carried out by treating the symptoms of the disease as they arise. Bone can be removed for esthetic reasons when needed.
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G L Ellis, P W Connole. 1985. Diffuse mandibular enlargement.. https://doi.org/10.14219/jada.archive.1985.0166
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