PubMed Health⌕ Search
Home/Archive/PubMed

PubMed · 3864787

Cefotiam susceptibility testing criteria.

P C Fuchs·A L Barry·R N Jones·C Thornsberry
View original source ↗Export metadata ↓

Abstract

Interpretive zone size breakpoints for diffusion tests with 30-micrograms cefotiam disks are diameters of greater than or equal to 18 mm for susceptible and less than or equal to 14 mm for resistant strains. The standard control strains Escherichia coli ATCC 25922 and Staphylococcus aureus ATCC 25923 should both give zones 27 to 33 mm in diameter. Tests with 579 clinical isolates yielded an unacceptably high rate of very major discrepancies between disk tests and microdilution tests; such discrepancies were especially common among Enterobacter spp. Additional studies support the concept that standard microdilution tests and standard disk diffusion tests may fail to detect a potential for resistance among some microorganisms.

Explore related subjects

CefotaximeCefotiamDrug Resistance, MicrobialEnterobacterEnterobacteriaceaeMicrobial Sensitivity TestsReference StandardsSpecies SpecificityComparative StudyJournal Article

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

P C Fuchs, A L Barry, R N Jones, C Thornsberry. 1985. Cefotiam susceptibility testing criteria.. https://doi.org/10.1128/jcm.22.6.1045-1047.1985

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

PubMed2006

Serotype distribution and antimicrobial susceptibility of S. pneumoniae causing invasive disease in Thai children younger than 5 years old, 2000-2005.

In order to predict the potential benefit of pneumococcal conjugate vaccines (PCV), we evaluated the serotype coverage of the 7-, 9-, 11- and 13-valent PCV over the isolates causing invasive pneumococcal disease (IPD) in Thai children. One hundred and fifteen Streptococcus pneumoniae isolates from sterile sites in children younger than 5 years old between 2000 and 2005 were serotyped. The coverages of 7-, 9-, 11-, and 13-valent PCV were 69%, 73.8%, 73.8% and 85.7% in children younger than 2 years, and 73.9%, 77.4%, 77.4% and 87.8% in children younger than 5 years of age, respectively. 69.6% and 22.6% of the isolates were non-susceptible to penicillin and cefotaxime. 7-valent PCV covered 89% and 100% of penicillin and cefotaxime non-susceptible isolates.

Cefotaxime↗
PubMed2006

A nosocomial outbreak of Escherichia coli producing CTX-M-15 and OXA-30 beta-lactamase.

During a survey of the prevalent subtypes of extended-spectrum beta -lactamases in a university hospital in Korea, a nosocomial outbreak of Escherichia coli producing CTX-M-15 and OXA-30 beta -lactamases was detected. The outbreak comprised various infections, including bloodstream infections and colonization, and persisted for several months in various areas of the hospital.

Cefotaxime↗