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Variation in human platelet 3H-imipramine binding.

S W Tang·J M Morris
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Abstract

Platelet 3H-imipramine binding values from 45 normal controls and 20 depressed subjects were collected over a 2-year period. During this time, wide inter-individual variations in the affinity constant (Kd) and maximal number of binding sites (Bmax) were observed in the control population; however, we failed to observe a seasonal change in platelet 3H-imipramine binding. The Kd and Bmax values of depressed subjects were not significantly different from those of controls.

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Binding SitesBlood PlateletsDepressive DisorderGenetic VariationHumansImipramineLongitudinal StudiesSeasonsJournal ArticleResearch Support, Non-U.S. Gov't

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S W Tang, J M Morris. 1985. Variation in human platelet 3H-imipramine binding.. https://doi.org/10.1016/0165-1781(85)90007-1

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