Identification and comparison of two sequence elements that confer cell-type specific transcription in yeast.

A M Miller; V L MacKay; K A Nasmyth

doi:10.1038/314598a0

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Identification and comparison of two sequence elements that confer cell-type specific transcription in yeast.

A M Miller·V L MacKay·K A Nasmyth

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Abstract

The MAT alpha 2 protein of budding yeast represses a set of genes; if the MATa1 protein is also present, a further set of genes is repressed. DNA sequence comparisons reveal a 20-base pair 'operator' sequence that is present in genes repressed by a1/alpha 2. A related, but distinct, sequence is found in genes repressed by alpha 2 alone.

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Base Sequence DNA, Fungal Gene Expression Regulation Genes, Fungal Mating Factor Peptides Promoter Regions, Genetic Repressor Proteins Saccharomyces cerevisiae Transcription, Genetic Journal Article

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A M Miller, V L MacKay, K A Nasmyth. Identification and comparison of two sequence elements that confer cell-type specific transcription in yeast.. https://doi.org/10.1038/314598a0

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