A human autoantibody to peroxisomes.

R Holm; P I Gaarder; L Helgeland; E I Falkenhaug

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PubMed · 3899430

A human autoantibody to peroxisomes.

R Holm·P I Gaarder·L Helgeland·E I Falkenhaug

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Abstract

A complement fixing, non-organ specific IgG autoantibody is described in 29 patients. The autoantibody gives a highly characteristic, granular staining of liver cells, proximal kidney tubules and stomach surface epithelium. By studies with various subcellular fractions from rat liver, employing two different techniques (quantitative complement fixation, and absorption combined with indirect immunofluorescence) the autoantibody was shown to react with a peroxisomal antigen. No convincing clinical correlations were found.

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Animals Autoantibodies Complement Fixation Tests Female Fluorescent Antibody Technique Gastric Mucosa Humans Immunoglobulin G Kidney Tubules Liver Male Mice Microbodies Microsomes Middle Aged Subcellular Fractions Journal Article

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R Holm, P I Gaarder, L Helgeland, E I Falkenhaug. 1985. A human autoantibody to peroxisomes.. https://pubmed.ncbi.nlm.nih.gov/3899430/

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