Human c-f gr gene does not contain coding sequence for actin-like protein.

M Nishizawa; K Semba; T Yamamoto; K Toyoshima

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PubMed · 3922831

Human c-f gr gene does not contain coding sequence for actin-like protein.

M Nishizawa·K Semba·T Yamamoto·K Toyoshima

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Abstract

f gr is a member of the protein kinase oncogene family and was found to have the highest homology to yes gene among the members of the family. Using a v-yes probe, a molecular clone of human c-f gr locus was isolated from a genomic library. Nucleotide sequence determination revealed that the actin gene-like sequence found in v-f gr gene was absent at the corresponding position of the c-f gr gene. Thus, the v-f gr gene product is considered to be a tri-chimeric gene product consisting of viral gag gene and two distinct cellular genes, actin gene and the proto-f gr gene.

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Actins Base Sequence Carcinogens Genetic Code Humans Protein Kinases Journal Article Research Support, Non-U.S. Gov't

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M Nishizawa, K Semba, T Yamamoto, K Toyoshima. 1985. Human c-f gr gene does not contain coding sequence for actin-like protein.. https://pubmed.ncbi.nlm.nih.gov/3922831/

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