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Mapping genetic systems by the supratype method.

N E Morton·R Lew
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Abstract

Kinship mapping and population supratypes provide information on order and relative genetic position of loci within a system too small to map by recombination. These methods are compared for the RH, beta-globin, HLA, and GM systems, where recombination between loci is estimated as 0.0002-0.0069. Supratype analysis does not appreciably improve kinship mapping. Mean recombination within systems appears to be 10(-4) morgans/kb, an order of magnitude greater than the average for the whole genome. Possible implications of this discrepancy are discussed.

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Chromosome MappingGenetic LinkageGenetics, PopulationGlobinsHLA AntigensHumansImmunoglobulin GModels, GeneticRh-Hr Blood-Group SystemJournal ArticleResearch Support, U.S. Gov't, P.H.S.

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N E Morton, R Lew. 1985. Mapping genetic systems by the supratype method.. https://doi.org/10.1007/bf00273447

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