Ectopic action potential generation: its occurrence in a chronic epileptogenic focus.

D Pinault; R Pumain

doi:10.1007/bf00236948

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Ectopic action potential generation: its occurrence in a chronic epileptogenic focus.

D Pinault·R Pumain

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Abstract

Intracortical axon terminals of thalamocortical relay neurons projecting into chronic cortical epileptogenic foci may generate high frequency bursts of action potentials during spontaneous cortical epileptiform paroxysms. Such bursts occur regularly before onset of the corresponding surface paroxysms in a large proportion of the tested neurons. Therefore, such axon terminals bursting may participate in the triggering of the synchronous, prolonged intracellular depolarization shifts which are observed in cortical neurons during epileptic events.

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Action Potentials Animals Cerebral Cortex Chronic Disease Disease Models, Animal Electroencephalography Epilepsies, Partial Male Neurons Rats Rats, Inbred Strains Reaction Time Thalamus Journal Article Research Support, Non-U.S. Gov't

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D Pinault, R Pumain. 1985. Ectopic action potential generation: its occurrence in a chronic epileptogenic focus.. https://doi.org/10.1007/bf00236948

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