PubMed HealthSearch

PubMed · 3952549

Mesenteric artery aneurysms.

Abstract

In this case of atherosclerotic aneurysm involving the main superior mesenteric artery and an aberrant artery from the aorta, characteristic eggshell calcifications were visible on preoperative x-ray films of the abdomen. The aneurysm was excised. Flow through the superior mesenteric artery was maintained by lateral suture of the artery at the site of excision of the aneurysm.

Explore related subjects

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

B E Ferrara. 1986. Mesenteric artery aneurysms.. https://doi.org/10.1097/00007611-198603000-00026

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

Mechanistic insights into Claudin-14 dysfunction implicated in veins of Galen malformation.

Claudin-14 (CLDN14) is a key component of tight junctions (TJs) critical for maintaining paracellular barrier function. Variants of CLDN14 have been linked to Vein of Galen malformations (VOGMs), a rare cerebrovascular disorder; however, the molecular mechanisms underlying their pathogenicity remain unknown. Here, we investigate the mechanistic effects of two VOGM-associated mutations, A113P and V143M, using reinforcement-learning driven enhanced sampling molecular dynamics simulations combined with DiffNets-based deep learning and independent trajectory-wide structural analyses. Our analysis reveals that A113P induces broader structural disruption of CLDN14, perturbing paracellular sealing, pore symmetry, and inter-protomer communication, whereas V143M induces structural rearrangements centred around TM3 and the TM3-ECL2 region. In both cases, mutation-specific alterations are observed in structural stability and interfacial organization across oligomeric assemblies. Notably, these effects are qualitatively consistent across different modelled architectures, despite variability in local responses. In the absence of experimentally resolved structures, the structural perturbations reported here provide a mechanistic understanding of how VOGM-associated variants may influence CLDN14 structure and dynamics.

Aneurysm