Intermembrane linkage mediated by tubulin.

P Vassilev; M Kanazirska; H T Tien

doi:10.1016/0006-291x(85)90642-4

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Intermembrane linkage mediated by tubulin.

P Vassilev·M Kanazirska·H T Tien

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Abstract

Two membranes from brain lipids were formed in the presence of brain tubulin and their electrical potentials were simultaneously measured. When electrical pulses were applied across one of them, displacements of the potential of the other membrane were found even when the membranes were not in contact. This effect was observed only in the presence of polymerized tubulin. It was not found in the presence of depolymerized tubulin or in other control experiments. The findings suggest that the microtubule fiber networks may serve as an interconnecting system between membranes or membrane bounded compartments.

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Animals Brain Chemistry Electric Stimulation Guanosine Triphosphate Lipid Bilayers Lipid Metabolism Polymers Time Factors Tubulin Journal Article Research Support, U.S. Gov't, P.H.S.

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P Vassilev, M Kanazirska, H T Tien. 1985-01-16. Intermembrane linkage mediated by tubulin.. https://doi.org/10.1016/0006-291x(85)90642-4

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