Cross-linking with dimethylsuberimidate to study thyroglobulin conformation.

B Di Jeso; S Formisano; G Palumbo

doi:10.1016/s0006-291x(85)80122-4

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Cross-linking with dimethylsuberimidate to study thyroglobulin conformation.

B Di Jeso·S Formisano·G Palumbo

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Abstract

The present investigation demonstrates that the cross-linking agent, dimethylsuberimidate, is an usefull tool to study thyroglobulin structure. In fact, while reproducible and discrete polymerization products are obtained in strictly controlled conditions, valuable information on the native assemblage of thyroglobulin subunits and the effects of its major post-translational modification (iodination) on its structure, are reported.

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Animals Chemical Phenomena Chemistry Dimethyl Suberimidate Electrophoresis, Polyacrylamide Gel Imidoesters Molecular Weight Protein Conformation Thyroglobulin Journal Article

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B Di Jeso, S Formisano, G Palumbo. 1985-02-28. Cross-linking with dimethylsuberimidate to study thyroglobulin conformation.. https://doi.org/10.1016/s0006-291x(85)80122-4

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