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PubMed · 4013552

[Anesthesia in cesarean section].

Abstract

667 cases inclusively 27 twin-births are evaluated in a retrospective study on the anesthesias administered in cesarean section (CS) from 1975 to 1983. The applied induction anesthetics hexobarbital, ketamine (Ketanest), propanidid (Sombrevin), etomidate (Radenarcon) and epidural anesthesia with bupivacaine (Marcaine) have been compared with each other concerning the Apgar scores of the newborns. Significant more depressed newborns have been found both in the hexobarbital group and to a low degree in the ketamine group. This tendency is also preserved when only the primary CS are taken into consideration. Besides the indications for the single anesthetics and methods of anesthesia, respectively, reference is made to the positioning of the mother and the avoidance of aspiration in the introduction of the anesthesia.

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BibTeXRIS

K Siegismund, M Beutner. 1985. [Anesthesia in cesarean section].. https://pubmed.ncbi.nlm.nih.gov/4013552/

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Electrophysiological evaluation of spinal reflexes during epidural anesthesia in an experimental model.

We assessed the effects of epidural anesthesia with bupivacaine in the rat by serial recordings of spinal reflexes. The H wave from plantar muscles after electrical stimulation of the sciatic nerve evaluates a large nerve fiber spinal reflex arch. The extensor reflex response recorded from quadriceps muscle after stimulation of the contralateral tibial nerve assesses a reflex arch with small fiber afferents. After epidural injection of 0.2 mL of bupivacaine (0.25%, 0.5%, and 1.0% solutions) at the L5-L6 vertebral space, nociceptive, H, and extensor reflex responses were abolished within 1-3 min. Duration of complete blockade lasted 20-80 min, increasing with the anesthetic concentration, and complete recovery occurred after an additional period of 30-40 min. The responses recovered to amplitudes similar to preanesthesia controls, indicating that there was no damage to the nervous system. This study shows that electrophysiological recording and quantitation of nerve reflex responses is a useful and accurate method to evaluate the efficacy of local anesthetic agents.

Anesthesia, Epidural