Tumour-host metabolic interaction and cachexia.

P A Lazo

doi:10.1016/0014-5793(85)81239-4

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Tumour-host metabolic interaction and cachexia.

P A Lazo

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Abstract

Cachexia is a terminal metabolic problem observed in a wide variety of tumours. In this article I propose that the syndrome is a direct consequence of the common feature to all malignant tumours: growth. I suggest that the requirement for essential amino acids can be used as the unifying principle that links the tumour to the two main components of cachexia: muscle wastage and anorexia. This underlying factor is usually clouded by the overlapping of individual tumour characteristics.

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Amino Acids Cachexia Cell Division Humans Leucine Models, Biological Neoplasm Proteins Neoplasms Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

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P A Lazo. 1985-08-05. Tumour-host metabolic interaction and cachexia.. https://doi.org/10.1016/0014-5793(85)81239-4

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