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PubMed · 402420

Histaminase release from human eosinophils.

R S Zeiger·H R Colten
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Abstract

Phagocytosis of opsonized zymosan by human eosinophils results in a dose-dependent noncytotoxic release of histaminase as well as arylsulfatase and beta-glucuronidase. The calcium ionophore A23187 also stimulates release of eosinophil histaminase at concentrations of ionophore which barely release arylsulfatase and beta-glucuronidase. Zymosan-induced histaminase release from eosinophils but not from neutrophils was abolished or markedly reduced in the presence of cytochalasin B, suggesting a difference in the mechanisms of histaminase release from the two granulocyte cell types.

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Amine Oxidase (Copper-Containing)ArylsulfatasesCalcimycinCytochalasin BEosinophilsGlucuronidaseHumansOpsonin ProteinsZymosanJournal ArticleResearch Support, U.S. Gov't, P.H.S.

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R S Zeiger, H R Colten. 1977. Histaminase release from human eosinophils.. https://pubmed.ncbi.nlm.nih.gov/402420/

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