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PubMed · 4034639

[Dissolution processes and surface alteration. 4. Determination of the "effective" surface].

R Neubert·W Fürst·H Frenzel·U Weber
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Abstract

A method is described for measuring the "effective" surface of a drug by means of dissolution parameters using the Paddle-model or a resorption-model respectively. The obtained values were compared with the specific surface which was determined by BET-technique. The "effective" surfaces obtained by means of the dissolution parameters are smaller than those determined BET-technique.

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DiffusionKineticsModels, ChemicalPhenobarbitalPhenytoinSalicylatesSalicylic AcidSolubilitySurface PropertiesEnglish AbstractJournal Article

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R Neubert, W Fürst, H Frenzel, U Weber. 1985. [Dissolution processes and surface alteration. 4. Determination of the "effective" surface].. https://pubmed.ncbi.nlm.nih.gov/4034639/

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