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PubMed · 4050983

Cryptococcal meningitis: presentation as sudden deafness.

M J Maslan·M D Graham·L M Flood
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Abstract

A patient presented with a bilateral profound hearing loss of sudden onset following a two-month neurologic illness. Microscopy and culture of cerebrospinal fluid revealed Cryptococcus neoformans. Treatment with amphotericin B and 5-fluorocytosine failed to restore hearing. Auditory brain stem response and electrical promontory stimulation suggest a profound deafness with poor neuronal survival. This is consistent with previous temporal bone histopathology reports in individuals dying of cryptococcal meningitis, suggesting a retrocochlear lesion. It is important to exclude this occult pathologic factor in a patient with the sudden onset of sensorineural deafness prior to embarking upon a course of steroid therapy.

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Amphotericin BAudiometry, Evoked ResponseCryptococcosisElectronystagmographyEvoked Potentials, AuditoryFemaleFlucytosineHearing Loss, SuddenHumansMeningitisMiddle AgedCase ReportsJournal Article

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M J Maslan, M D Graham, L M Flood. 1985. Cryptococcal meningitis: presentation as sudden deafness.. https://pubmed.ncbi.nlm.nih.gov/4050983/

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