PubMed · 4065490
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P Marcellin, S Erlinger. 1985. [Benign recurrent cholestasis].. https://pubmed.ncbi.nlm.nih.gov/4065490/
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To assess the outcomes after pancreatic cancer treatment in a nationwide hospital system, patients treated in Department of Veterans Affairs (DVA) hospitals from 1987 to 1991 were studied by tumor stage, the most significant reported influence on survival. Tumor registrars from DVA hospitals provided information that allowed TNM staging in 598 patients, and duration of survival from treatment to death was known in 96+% of cases. Survival was 9 months longer after 64 resections for stage I-II (localized) pancreatic cancer than after 149 other treatments (P < 0.05, ANOVA), but resection did not increase mean survival in 49 patients with stage III (lymph node metastases) disease. Twenty-one patients with ampullary, duodenal, bile duct, or cystic cancers had a significantly increased survival at any stage, but this may be due to the selection of sicker patients for nonoperative therapies.
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The diagnosis of hepatobiliary disorders is based on the patient's history and physical examination and is augmented by laboratory findings, imaging studies, and histology. Radiographic imaging is especially helpful for identifying structural lesions and vascular abnormalities. In cholestatic disease, imaging of the biliary tree is essential to identify extrahepatic biliary obstruction. In hepatocellular diseases, imaging studies narrow the differential diagnosis and guide further testing. In this clinical overview, the role of radiographic imaging in hepatobiliary disorders is reviewed.