[Thyroid and C-cell system function during prolonged rotation (morphobiochemical research)].

G I Plakhuta-Plakutina; E A Savina; B V Afonin

PubMed · 4087862

[Thyroid and C-cell system function during prolonged rotation (morphobiochemical research)].

G I Plakhuta-Plakutina·E A Savina·B V Afonin

Abstract

The thyroid and parathyroid glands of 65 Wistar rats centrifuged for 30 days at 1.1 and 2.0 G were examined histologically and biochemically. The centrifugation led to a higher activity to C-cells, an increased rate of thyro-calcitonin (TCT) synthesis and excretion, i.e. C-cell degranulation, and a significant (two-fold) increase of TCT in plasma. The stimulation effect of the TCT-producing system persisted during 7-post-rotation days and was very distinct in the animals exposed to 2.0 G. There were no morphological changes in the parathyroid glands or in the PTH concentration in the plasma.

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Animals Calcitonin Colloids Histocytochemistry Parathyroid Glands Parathyroid Hormone Rats Rats, Inbred Strains Rotation Thyroid Gland Time Factors Weightlessness Comparative Study English Abstract Journal Article

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G I Plakhuta-Plakutina, E A Savina, B V Afonin. [Thyroid and C-cell system function during prolonged rotation (morphobiochemical research)].. https://pubmed.ncbi.nlm.nih.gov/4087862/

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