PubMed · 4121854
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1973-03-24. Britain 2001.. https://pubmed.ncbi.nlm.nih.gov/4121854/
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Number and sex of offspring were determined in a group of 7,841 randomly selected blood donors who were screened for the delta F508 mutation. We did not find any evidence for differences in number or sex ratio of offspring between delta F508 carriers and non-carriers.
The present paper offers data to suggest an effect of geographic latitude in regard to the frequency of conception in human populations. The birth statistics from eight countries in different parts of the world have been evaluated. A particularly strong minimum appears to occur in almost all regions but is shifted in time with changing latitude.
This report compares validity, precision and convenience of three frequently used parameters used to describe seasonality in reproductive outcome: prevalence, index and ratio observed versus expected. Each has its advantages and disadvantages; the choice of the parameter depends on the aim of the study. It is advisable to report the number of cases and referents per month, because all three parameters can be derived from this information.