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The type-specific substance from Pneumococcus type 33B.

M J Watson
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Abstract

1. The type-specific substance, S. 33B, from Pneumococcus type 33B contains P, 2.89; hexose, 51; total sugar, 69; galactosamine, 18; and d-glucose, 20%. 2. After degradation with alkali, followed by enzymic dephosphorylation, S. 33B yielded a hexasaccharide. 3. The hexasaccharide was assigned the structure O-beta-d-glucopyranosyl- (1-->5)-O-beta-d-galactofuranosyl- (1-->3)-O-2-acetamido-2-deoxy-beta-d- galactopyranosyl-(1-->4)-O-[alpha-d- galactopyranosyl-(1-->2)]-alpha-d-galactopyranosyl- (1-->2)-ribitol. 4. Phosphate residues in S. 33B are located on the hydroxyl groups at position 5 of ribitol units and on the hydroxyl groups at position 6 of hexopyranose residues.

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Chemical PhenomenaChemistryChromatography, PaperGalactosamineGlucoseHexosesHydrolysisImmune SeraImmunodiffusionMethylationPolysaccharides, BacterialRiboseSpecies SpecificityStreptococcus pneumoniaeStructure-Activity RelationshipSugar AlcoholsJournal Article

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M J Watson. 1974. The type-specific substance from Pneumococcus type 33B.. https://doi.org/10.1042/bj1370603

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