Mass spectrometric peptide sequencing: cyclochlorotine.

R J Anderegg; K Biemann; A Manmade; A C Ghosh

doi:10.1002/bms.1200060310

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Mass spectrometric peptide sequencing: cyclochlorotine.

R J Anderegg·K Biemann·A Manmade·A C Ghosh

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Abstract

A potent toxin isolated from Penicillium islandicum Sopp was found to have the composition C24H31N5O7Cl2. Mass spectrometric investigation of a partial acid hydrolyzate showed that it has the structure of cyclochlorotine. The mass spectral characteristics of polyamino alcohol-related derivatives of peptides containing beta-phenylalanine, alpha-amino butyric acid and dichloroproline were determined in the course of this work.

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Amino Acid Sequence Aminobutyrates Bacterial Toxins Chlorine Mass Spectrometry Mycotoxins Penicillium Peptides, Cyclic Phenylalanine Proline Journal Article Research Support, U.S. Gov't, P.H.S.

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R J Anderegg, K Biemann, A Manmade, A C Ghosh. 1979. Mass spectrometric peptide sequencing: cyclochlorotine.. https://doi.org/10.1002/bms.1200060310

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