PubMed · 4234938
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C C Johnson. 1968. Epicanthus.. https://doi.org/10.1016/0002-9394(68)92817-1
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A six-year-old boy consulted an ophthalmologist, because another boy had hit his right eye with a tree branch. There were slight corneal erosions, and a superficial small wound in the oedematous upper lid. The erosions healed in 2 days, but the lid showed progressive ptosis and oedema. Computed tomography revealed a hyperdense, tight structure, which was suspected to be a foreign particle. An orbital exploration was made three times, but the foreign body was not found. After prolonged suppuration, two wooden particles appeared spontaneously 4 and 5.5 months after the trauma. After that, the suppuration subsided and the wound healed.
Twenty patients with a diagnosis of Saethre-Chotzen syndrome had their cervical spine radiographs reviewed. Radiologic abnormalities including vertebral fusion were present in 9 of the 20 patients. Fusion of both the vertebral bodies and the posterior elements was noted, although the latter site was more common. C2-3 was the level most commonly involved, although other levels were recorded. Analysis of sequential radiographs in nine patients revealed evidence of progression in seven patients. In those studies in children aged under 2 years, only 1 of 18 films showed evidence of fusion, while in those over 2 years of age, 10 of 12 showed evidence of fusion. These results reveal that the incidence of cervical anomalies in Saethre-Chotzen syndrome is greater than that in the general population. There is both direct and indirect evidence that the vertebral fusions are progressive during childhood.
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