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Increased release of tumour cells by collagenase at acid pH: a possible mechanism for metastasis.

G A Turner
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Abstract

The ability of collagenase to disaggregate a solid metastasizing lymphosarcoma has been shown to considerably increase with reducing environmental pH. It is suggested that this effect may be operating in vivo to release cells from a primary tumour.

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AnimalsCricetinaeHydrogen-Ion ConcentrationLymphoma, Non-HodgkinMesocricetusMicrobial CollagenaseNeoplasm MetastasisNeoplasms, ExperimentalJournal Article

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G A Turner. 1979-12-15. Increased release of tumour cells by collagenase at acid pH: a possible mechanism for metastasis.. https://doi.org/10.1007/bf01953252

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