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The radiographic effect of cage subsidence on neuroforamina after anterior cervical discectomy and fusion.

Miles W A Fisher·Zachariah W Pinter·Hannah Levy·Colton Mowers·Christopher Kepler·Benjamin D Elder·Paul M Huddleston·Melvin Helgeson·Ahmad Nassr·Brett Freedman·Arjun Sebastian
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Abstract

STUDY DESIGN: Retrospective Cohort Study. OBJECTIVE: The objective of this study is to investigate the effect of cage subsidence on neuroforaminal area after anterior cervical discectomy and fusion (ACDF) utilizing computed tomography (CT). SUMMARY OF BACKGROUND DATA: Restoration of disc height via implantation of an interbody device provides an indirect decompression of the cervical neuroforamina. Interbody cage subsidence is a potential postoperative occurrence, but the effect of this on neuroforaminal area has yet to be characterized. METHODS: A retrospective review was conducted of patients who underwent one- to four-levels of ACDF utilizing an interbody device with anterior plating. Cage subsidence, neuroforaminal area, height and width were measured on CT scans preoperatively and at least 6&#xa0;months postoperatively. Levels with a cumulative sum of cranial and caudal subsidence greater than 4&#xa0;mm were classified as severely subsided, while levels with cumulative subsidence less than 4&#xa0;mm were classified as non-severely subsided. RESULTS: A total of 83 patients (151 levels) were included in this retrospective analysis. Average endplate subsidence was 3.2&#xa0;&#xb1;&#xa0;1.9&#xa0;mm. Non-severely subsided levels demonstrated a greater perioperative increase in neuroforaminal area (7.9 vs 2.1&#xa0;mm2, p&#xa0;<&#xa0;0.001), neuroforaminal height (1.1 vs 0.4&#xa0;mm, p&#xa0;<&#xa0;0.001) and neuroforaminal width (0.7 vs 0.1&#xa0;mm, p&#xa0;<&#xa0;0.001) compared to severely subsided levels. Interbody subsidence significantly predicted a decreased change in neuroforaminal height, width and area (p&#xa0;<&#xa0;0.001). Severe subsidence was associated with an increased rate of pseudarthrosis, but similar reoperation rates and recurrent neurologic deficits between the two groups. CONCLUSIONS: Severe subsidence of interbody cages after an ACDF was associated with a decreased perioperative change in neuroforaminal dimensions. This decrease in the size of the neuroforamen may reduce the effect of indirect decompression of the nerve root.

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HumansDiskectomySpinal FusionCervical VertebraeRetrospective StudiesFemaleMaleMiddle AgedAdultTomography, X-Ray ComputedPostoperative ComplicationsTreatment OutcomeAnterior cervical discectomy and fusionCervical radiculopathyInterbodyIntervertebral foramenSubsidenceJournal Article

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Miles W A Fisher, Zachariah W Pinter, Hannah Levy, Colton Mowers, Christopher Kepler, Benjamin D Elder, Paul M Huddleston, Melvin Helgeson, Ahmad Nassr, Brett Freedman, Arjun Sebastian. 2026-08-26. The radiographic effect of cage subsidence on neuroforamina after anterior cervical discectomy and fusion.. https://doi.org/10.1016/j.jocn.2026.112226

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