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Genetically Distinct African Swine Fever Virus Genotype II Variant in Wild Boar, Spain, 2025-2026.

Carmina Gallardo·Marina Marcet-Houben·Montserrat Agüero·Raquel Nieto·Nadia Casado·Alejandro Soler·María José Ruano·Rubén Villalba·Jovita Fernández-Pinero·Alicia Simón·Covadonga Pérez·Concepción Gómez·Cecilia García·Mireia Labrador·Jordi Argilaguet·Liani Coronado·Natàlia Majó·Pilar Aguilera-Sepulveda·Irene Aldea·Toni Gabaldón·María Belén Gómez·Marisa Arias
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Abstract

African swine fever virus genotype II was detected in wild boar in Spain in 2025 after >30 years of absence. Whole-genome sequencing and molecular follow-up of 8 representative cases identified a stable 9.8-kb deletion affecting the multigene family in the left variable region, defining an ASFV genotype II variant.

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AnimalsAfrican Swine Fever VirusSpainAfrican Swine FeverSus scrofaGenotypeSwinePhylogenyGenome, ViralGenetic VariationWhole Genome SequencingAfrican swine fever virusgenotype IIleft variable regionmultigene typingviruseswhole-genome sequencingwild boarJournal Article

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Carmina Gallardo, Marina Marcet-Houben, Montserrat Agüero, Raquel Nieto, Nadia Casado, Alejandro Soler, María José Ruano, Rubén Villalba, Jovita Fernández-Pinero, Alicia Simón, Covadonga Pérez, Concepción Gómez, Cecilia García, Mireia Labrador, Jordi Argilaguet, Liani Coronado, Natàlia Majó, Pilar Aguilera-Sepulveda, Irene Aldea, Toni Gabaldón, María Belén Gómez, Marisa Arias. 2026. Genetically Distinct African Swine Fever Virus Genotype II Variant in Wild Boar, Spain, 2025-2026.. https://doi.org/10.3201/eid3209.260360

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