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PubMed · 4307976

Human granulocyte collagenase.

G S Lazarus·R S Brown·J R Daniels·H M Fullmer
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Abstract

A collagenase, operative at neutral and alkaline pH, has been extracted from the granule fraction of human granulocytic leukocytes. It digests reconstituted collagen fibrils and reduces the viscosity of collagen solutions. Cleavage of collagen in solution with purified enzyme produces the discrete products characteristic of other animal collagenases.

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Acrylic ResinsArthus ReactionCarbon IsotopesCollagenCytoplasmic GranulesElectrophoresisGelsHumansHydrogen-Ion ConcentrationInflammationLeukocytesLymphocytesMicrobial CollagenaseNeutrophilsViscosityJournal Article

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G S Lazarus, R S Brown, J R Daniels, H M Fullmer. 1968-03-29. Human granulocyte collagenase.. https://doi.org/10.1126/science.159.3822.1483

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