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PubMed · 4322346

D-Mannitol utilization in Salmonella typhimurium.

D Berkowitz
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Abstract

A biochemical and genetic analysis of d-mannitol metabolism in Salmonella typhimurium indicates that d-mannitol is phosphorylated by the phosphoenolpyruvate-dependent phosphotransferase system. d-Mannitol-1-phosphate is converted to d-fructose-6-phosphate by mannitol-1-phosphate dehydrogenase. Two classes of mannitol mutants are described. Both map at about 115 min on the Salmonella chromosome. Mutants missing mannitol-1-phosphate dehydrogenase activity are mannitol sensitive; i.e., either growth is inhibited or the cells are lysed in the presence of mannitol. In a strain missing adenyl cyclase activity, the mannitol genes require exogenous cyclic adenosine-3',5'-monophosphate for expression.

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Adenine NucleotidesAlcohol OxidoreductasesCarbon IsotopesChromosome MappingCulture MediaCyclic AMPJournal Article

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BibTeXRIS

D Berkowitz. 1971. D-Mannitol utilization in Salmonella typhimurium.. https://doi.org/10.1128/jb.105.1.232-240.1971

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