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A rapid, simple assay for digoxin.

H Greenwood·M Howard·J Landon
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Abstract

An extremely rapid radioimmunoassay for digoxin is described which is precise over the range of concentrations required to determine whether, or not, a patient has digoxin toxicity. The assay is based on the use of (125)-iodine-labelled digoxin and of a gel equilibration technique for the separation of antibody-bound and free digoxin. The results obtained compare closely with those by a conventional radioimmunoassay and the technique is sufficiently simple to enable its performance by relatively inexperienced laboratory staff.

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Binding Sites, AntibodyDigoxinHumansImmune SeraIodine RadioisotopesRadioimmunoassayJournal Article

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BibTeXRIS

H Greenwood, M Howard, J Landon. 1974. A rapid, simple assay for digoxin.. https://doi.org/10.1136/jcp.27.6.490

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