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Ly-4, a new locus determining a lymphocyte cell-surface alloantigen in mice.

G D Snell·M Cherry·I F McKenzie·D W Bailey
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Abstract

A new locus is described that determines an alloantigen on the surface of lymphocytes. It differs from loci previously described in that the corresponding antibody, at least in most antisera, reacts almost exclusively with node lymphocytes, and weakly or not at all with thymuslymphocytes. Positive strains include C57BL/6, C57BL/10, C57L, C57BR/cd, and RF; negative strains include BALB/c, C3H, and SJL. The symbol Ly-4 is assigned, with the C57BL/6 allele being Ly-4(b), and the BALB/c allele Ly-4(a).

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AnimalsAntigen-Antibody ReactionsCell MembraneChromosome MappingCrosses, GeneticCytotoxicity Tests, ImmunologicGenesGenetic LinkageHemagglutination TestsHistocompatibility AntigensImmunizationIsoantigensLymphocytesMiceMice, Inbred BALB CMice, Inbred C3HMice, Inbred C57BLMice, Inbred StrainsRecombination, GeneticSpleenSubmandibular GlandThymus GlandJournal Article

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G D Snell, M Cherry, I F McKenzie, D W Bailey. 1973. Ly-4, a new locus determining a lymphocyte cell-surface alloantigen in mice.. https://doi.org/10.1073/pnas.70.4.1108

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