Immunoglobulin A: site and sequence of expression in developing chicks.

P W Kincade; M D Cooper

doi:10.1126/science.179.4071.398

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Immunoglobulin A: site and sequence of expression in developing chicks.

P W Kincade·M D Cooper

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Abstract

Synthesis of immunoglobulins A, G, and M (IgA, IgG, and IgM) is prevented in chickens by embryonic treatment with heterologous antibodies to IgM when combined with bursectomy at hatching. Cells that produce IgA are seeded from the bursa of Fabricius later than cells capable of IgM and IgG synthesis; the latter do not convert to IgA synthesis outside of the bursa.

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Animals Antibodies, Anti-Idiotypic Antibody-Producing Cells B-Lymphocytes Bursa of Fabricius Chick Embryo Fluorescent Antibody Technique Immunoglobulin A Immunoglobulin G Immunoglobulin M Journal Article

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P W Kincade, M D Cooper. 1973-01-26. Immunoglobulin A: site and sequence of expression in developing chicks.. https://doi.org/10.1126/science.179.4071.398

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