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PubMed · 46237

Carrier-determined tolerance in vitro.

P Galanaud·M Aldo-Benson·Y Borel
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Abstract

A primary immune response to normal BDF1 spleen cells was obtained in vitro to the T-independent antigen TNP-T4 coliphage. This anti-TNP response was suppressed by exposing the spleen cells for 6 hr to TNP bound either to isologous or heterologous gamma-globulin. The suppression was hapten specific. In contrast, TNP-albumin conjugates did not induce tolerance in vitro.

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AnimalsCarrier ProteinsCattleCells, CulturedColiphagesErythrocytesHaptensHemolytic Plaque TechniqueHumansImmune ToleranceLymphocytesMaleMiceMice, Inbred DBANitrophenolsRabbitsSerum Albumin, BovineSheepSpleenThymus Glandgamma-GlobulinsJournal ArticleResearch Support, U.S. Gov't, Non-P.H.S.

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P Galanaud, M Aldo-Benson, Y Borel. 1975. Carrier-determined tolerance in vitro.. https://pubmed.ncbi.nlm.nih.gov/46237/

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