PubMed · 464006
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E Cotlier. 1979. Pigmented retinochoroidal atrophy.. https://doi.org/10.1016/0002-9394(79)90774-8
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A cavernous angioma of the cerebellum occurred in a 55-year-old female presenting with a 3-year history of slowly progressive cerebellar signs and symptoms. Computed tomography and magnetic resonance imaging revealed a lesion in the left cerebellar nuclei and atrophic change of the affected cerebellar hemisphere. The final diagnosis was made at operation. The cerebellar nuclei and white matter were probably affected by the slowly expanding lesion, with repeated hemorrhage leading to degeneration of the afferent and efferent fibers, and subsequent atrophy of the affected cerebellar hemisphere.
Anti-keratin and PAP immunohistochemical reaction on atrophic thymus collected from 97 autopsies were studied. Among them, 61 cases belonged to the severs type, whose reticulo-epithelial cells were falling into 4 types: the normal type, the centrally focused type, the diffused type and the depletive type. In 37 out of 61 cases, the reticulo-epithelial cells showed proliferation, especially in the medullary zone. All of 7 cases known as physiological involutional thymus turned to depletive type. 11 cases of atrophic thymus studied by scanning electron microscopy had been classified morphologically into 3 patterns, namely: the reticular form, the honey-combed form and the depletive form respectively.
We report a case of steatorrhoea and sub-total villous atrophy, occurring during therapy with mefenamic acid. The patient recovered on cessation of the drug while continuing a normal diet.