PubMed · 4669988
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W R Miller. 1972. Editorial: Regionalization in Minnesota.. https://pubmed.ncbi.nlm.nih.gov/4669988/
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Evidence suggests that Shiga toxin-producing Escherichia coli (STEC) strains do not persist at the farm level. We hypothesized that ecosystem-level STEC persistence occurs and contributes significantly to disease burden. We tested this by identifying locally persistent lineages (LPLs) of STEC O157:H7 in Minnesota. We identified 15 distinct LPLs, which were associated with 35.3% of reported cases in Minnesota and persisted for 1.3-8.6 years. Locally persistent lineages were associated with multiple outbreaks with Minnesota sources and no multi-state outbreaks, and LPL cases were spatially clustered. Our findings show long-term persistence in defined geographic areas, suggesting the importance of ecosystem-level persistence.
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This report summarizes Mayo Clinic Rochester's experience with a picture archiving and communication system (PACS) to date and discusses the principles that have guided implementation.