Complement-induced platelet protein alterations.

T S Zimmerman; H J Müller-Eberhard

doi:10.1126/science.180.4091.1183

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PubMed · 4707064

Complement-induced platelet protein alterations.

T S Zimmerman·H J Müller-Eberhard

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Abstract

Polypeptides of high molecular weight are deleted from the sedimentable fraction of platelets subjected, while intact, to complement action. These polypeptides, distinct from the previously described thrombin-sensitive protein of this fraction, also diminish after platelets are exposed to thrombin. They may be of importance in the molecular events underlying complement-triggered changes in platelet function.

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Animals Blood Platelets Blood Proteins Complement System Proteins Electrophoresis, Polyacrylamide Gel Humans Molecular Weight Peptides Rabbits Thrombin Journal Article

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T S Zimmerman, H J Müller-Eberhard. 1973-06-15. Complement-induced platelet protein alterations.. https://doi.org/10.1126/science.180.4091.1183

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